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Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B
As current interventions for chronic hepatitis B (CHB) rarely induce cure, more effective drugs are needed. Short-term treatment of woodchucks with the novel immunomodulator AIC649, a parapoxvirus-based stimulator of toll-like receptor 9 dependent and independent pathways, has been shown to reduce v...
Autores principales: | Korolowicz, Kyle E., Suresh, Manasa, Li, Bin, Huang, Xu, Yon, Changsuek, Leng, Xuebing, Kallakury, Bhaskar V., Tucker, Robin D., Menne, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069054/ https://www.ncbi.nlm.nih.gov/pubmed/33918831 http://dx.doi.org/10.3390/v13040648 |
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