DNA2 in Chromosome Stability and Cell Survival—Is It All about Replication Forks?

The conserved nuclease-helicase DNA2 has been linked to mitochondrial myopathy, Seckel syndrome, and cancer. Across species, the protein is indispensable for cell proliferation. On the molecular level, DNA2 has been implicated in DNA double-strand break (DSB) repair, checkpoint activation, Okazaki f...

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Detalles Bibliográficos
Autores principales: Hudson, Jessica J. R., Rass, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069077/
https://www.ncbi.nlm.nih.gov/pubmed/33924313
http://dx.doi.org/10.3390/ijms22083984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069077/
https://www.ncbi.nlm.nih.gov/pubmed/33924313
http://dx.doi.org/10.3390/ijms22083984

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