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DNA2 in Chromosome Stability and Cell Survival—Is It All about Replication Forks?
The conserved nuclease-helicase DNA2 has been linked to mitochondrial myopathy, Seckel syndrome, and cancer. Across species, the protein is indispensable for cell proliferation. On the molecular level, DNA2 has been implicated in DNA double-strand break (DSB) repair, checkpoint activation, Okazaki f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069077/ https://www.ncbi.nlm.nih.gov/pubmed/33924313 http://dx.doi.org/10.3390/ijms22083984 |