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Synthesis and Evaluation of Novel Norfloxacin Isonitrile (99m)Tc Complexes as Potential Bacterial Infection Imaging Agents

To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [(99m)Tc][Tc(I)](+) core to obtain [(99m)Tc]Tc-CN4NF and [(99m)...

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Detalles Bibliográficos
Autores principales:	Fang, Si’an, Jiang, Yuhao, Xiao, Di, Zhang, Xuran, Gan, Qianqian, Ruan, Qing, Zhang, Junbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069222/ https://www.ncbi.nlm.nih.gov/pubmed/33918583 http://dx.doi.org/10.3390/pharmaceutics13040518

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