Cargando…

An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives

Pyrrolo[3,4-c]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-c]pyridine derivatives is the main reason for developing new compounds containing this scaf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wójcicka, Anna, Redzicka, Aleksandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069244/ https://www.ncbi.nlm.nih.gov/pubmed/33920479 http://dx.doi.org/10.3390/ph14040354

Ejemplares similares

Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX Inhibitors
por: Mikus, Jakub, et al.
Publicado: (2023)

Interactions of N-Mannich Bases of Pyrrolo[3,4-c]pyrrole with Artificial Models of Cell Membranes and Plasma Proteins, Evaluation of Anti-Inflammatory and Antioxidant Activity
por: Szczukowski, Łukasz, et al.
Publicado: (2023)

Nature of Linear Spectral Properties and Fast Electronic Relaxations in Green Fluorescent Pyrrolo[3,4-c]Pyridine Derivative
por: Bashmakova, Nataliia V., et al.
Publicado: (2021)

Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones Derivatives
por: Krzyżak, Edward, et al.
Publicado: (2020)

Bioresearch of New 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones
por: Szkatuła, Dominika, et al.
Publicado: (2020)

Design, Synthesis, Biological Evaluation, and Molecular Docking Study of 4,6-Dimethyl-5-aryl/alkyl-2-[2-hydroxy-3-(4-substituted-1-piperazinyl)propyl]pyrrolo[3,4-c]pyrrole-1,3(2H,5H)-diones as Anti-Inflammatory Agents with Dual Inhibition of COX and LOX
por: Redzicka, Aleksandra, et al.
Publicado: (2023)

Synthesis and Antiproliferative Activity of Thiazolyl-bis-pyrrolo[2,3-b]pyridines and Indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, Nortopsentin Analogues
por: Carbone, Anna, et al.
Publicado: (2015)

6,6′-(Pyridine-2,6-diyl)bis(pyrrolo[3,4-b]pyridine-5,7-dione)
por: Van der Berg, P. C. W., et al.
Publicado: (2011)

Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles
por: Abunada, Nada M., et al.
Publicado: (2008)

Pyrrolo[3,2-c]pyridine derivatives with potential inhibitory effect against FMS kinase: in vitro biological studies
por: El-Gamal, Mohammed I., et al.
Publicado: (2018)

4-(1H-Pyrrolo[2,3-b]pyridin-2-yl)pyridine
por: Huang, Ping-Hsin, et al.
Publicado: (2013)

6-Benzyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-5,7-dione
por: Sun, Hong-Shun, et al.
Publicado: (2011)

Effect of Novel Pyrrolo[3,4-d]pyridazinone Derivatives on Lipopolysaccharide-Induced Neuroinflammation
por: Wakulik, Karolina, et al.
Publicado: (2020)

Synthesis of New Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy
por: Blanco-Carapia, Roberto E., et al.
Publicado: (2023)

Design and Synthesis of N-Substituted 3,4-Pyrroledicarboximides as Potential Anti-Inflammatory Agents
por: Redzicka, Aleksandra, et al.
Publicado: (2021)

1-Methyl-7-(4-nitrophenyl)-3-phenylpyrazolo[3,4-b]pyrrolo[3,4-d]pyridine-6,8(3H,7H)-dione
por: Sabino, Jose R., et al.
Publicado: (2008)

2-(1H-Pyrrolo[2,3-b]pyridin-2-yl)pyridine
por: Huang, Ping-Hsin, et al.
Publicado: (2012)

Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu Reaction and In Vitro–In Silico Studies against Breast Carcinoma
por: Morales-Salazar, Ivette, et al.
Publicado: (2023)

Biological Activity of Naturally Derived Naphthyridines
por: Chabowska, Gabriela, et al.
Publicado: (2021)

Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and of pyrrolo[1,2-a]phenanthrolines under mild conditions
por: Paira, Rupankar, et al.
Publicado: (2014)

Preparation and Physical Characterization of Pyrene and Pyrrolo[3,4‐c]pyrrole‐1,4‐dione‐Based Copolymers
por: Alqurashy, Bakhet A.
Publicado: (2019)

5-Bromo-1H-pyrrolo[2,3-b]pyridine
por: Štarha, Pavel, et al.
Publicado: (2013)

Synthesis and vectorial functionalisation of pyrazolo[3,4-c]pyridines
por: Bedwell, Elizabeth V., et al.
Publicado: (2023)

Access and Modulation of Substituted Pyrrolo[3,4-c]pyrazole-4,6-(2H,5H)-diones
por: Ejjoummany, Abdelaziz, et al.
Publicado: (2023)

Efficient synthesis of polyfunctionalized carbazoles and pyrrolo[3,4-c]carbazoles via domino Diels–Alder reaction
por: Fang, Ren-Jie, et al.
Publicado: (2021)

In Vitro and In Silico Evaluation of New 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone as Promising Cyclooxygenase Inhibitors
por: Peregrym, Krzysztof, et al.
Publicado: (2021)

New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity—Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies
por: Szczukowski, Łukasz, et al.
Publicado: (2021)

Design, synthesis and biological evaluation of 1H-pyrrolo[2,3-b]pyridine derivatives as potent fibroblast growth factor receptor inhibitors
por: Su, Xingping, et al.
Publicado: (2021)

Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives
por: Liu, Guan-Nan, et al.
Publicado: (2016)

2-(3,4,5-Trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
por: Selig, Roland, et al.
Publicado: (2009)

5-(4-Chlorophenyl)-6-isopropyl-5,6-dihydro-4H-pyrrolo[3,4-c]isoxazole
por: Ha, Kwang, et al.
Publicado: (2010)

Pyrazole‐promoted synthesis of pyrrolo[3,4‐c] quinoline-1,3‐diones in a novel diketene-based reaction
por: Rezvanian, Atieh, et al.
Publicado: (2023)

Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone Exert Antinociceptive Activity in the Tail-Flick and Formalin Test in Rodents and Reveal Reduced Gastrotoxicity
por: Szandruk-Bender, Marta, et al.
Publicado: (2020)

7-Bromo-3-ethyl-9-phenyl-2-tosylpyrrolo[3,4-b]quinoline
por: Sudha, D., et al.
Publicado: (2007)

4-Chloro-1-(4-methylphenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
por: Selig, Roland, et al.
Publicado: (2009)

2,5-Dihexyl-3,6-diphenylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
por: Sevinçek, Resul, et al.
Publicado: (2010)

Synthesis and biological activity of fused tetracyclic Pyrrolo[2,1-c][1,4]benzodiazepines
por: Annor-Gyamfi, Joel K., et al.
Publicado: (2018)

4-Chloro-7-methoxymethyl-2-phenyl-7H-pyrrolo[2,3-b]pyridine
por: Selig, Roland, et al.
Publicado: (2010)

Seven papers on fused-ring heterocyclic ketones containing an N-tosylpyrrolo[3,4-c]pyrano moiety. Corrigenda
por: Chinnakali, K., et al.
Publicado: (2007)

Synthesis and molecular modelling studies of pyrimidinones and pyrrolo[3,4-d]-pyrimidinodiones as new antiplasmodial compounds
por: Rogerio, Kamilla Rodrigues, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dsjf9k2eg45g2efrb4a51lu8q9