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Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity

Two DO3A-type ligands conjugated to substrates of urokinase (L3) and caspase-3 (L4) via a propyl-amide linker were synthesized and their lanthanide(III) (Ln(3+)) complexes studied. A model compound without peptide substrate (L2) and an amine derivative ligand mimicking the state after enzymatic clea...

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Detalles Bibliográficos
Autores principales:	Laine, Sophie, Morfin, Jean-François, Galibert, Mathieu, Aucagne, Vincent, Bonnet, Célia S., Tóth, Éva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069257/ https://www.ncbi.nlm.nih.gov/pubmed/33918899 http://dx.doi.org/10.3390/molecules26082176

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