Cargando…

Divergent Regulation of OCT and MATE Drug Transporters by Cadmium Exposure

Coordinated transcellular transport by the uptake via organic cation transporters (OCTs) in concert with the efflux via multidrug and toxin extrusion proteins (MATEs) is an essential system for hepatic and renal drug disposition. Despite their clinical importance, the regulation of OCTs and MATEs re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hong, Zhou, Shiwei, Guo, Dong, Obianom, Obinna N., Li, Qing, Shu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069296/ https://www.ncbi.nlm.nih.gov/pubmed/33924306 http://dx.doi.org/10.3390/pharmaceutics13040537

Ejemplares similares

Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-catenin Downregulation and AMPK Activation
por: Zhou, Shiwei, et al.
Publicado: (2021)

RETRACTED: Zhou et al. Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-Catenin Downregulation and AMPK Activation. Pharmaceutics 2021, 13, 330
por: Zhou, Shiwei, et al.
Publicado: (2023)

Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate)
por: Ceckova, Martina, et al.
Publicado: (2018)

Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity
por: Yang, Hong, et al.
Publicado: (2015)

A drug–drug interaction study to evaluate the impact of peficitinib on OCT1- and MATE1-mediated transport of metformin in healthy volunteers
por: Shibata, Mai, et al.
Publicado: (2020)

In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs
por: George, Blessy, et al.
Publicado: (2021)

Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [(11)C]Metoclopramide in Mice
por: Hernández-Lozano, Irene, et al.
Publicado: (2021)

Regulation of drug transporters in the testis by environmental toxicant cadmium, steroids and cytokines
por: Su, Linlin, et al.
Publicado: (2012)

Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia
por: Nishizawa, Kei, et al.
Publicado: (2019)

Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects
por: Topletz‐Erickson, Ariel R., et al.
Publicado: (2020)

Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells
por: Zhang, Xiaohong, et al.
Publicado: (2022)

Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2
por: Suo, Yang, et al.
Publicado: (2023)

Inhibitory Effects of Green Tea and (–)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein
por: Knop, Jana, et al.
Publicado: (2015)

PPAR-α Deletion Attenuates Cisplatin Nephrotoxicity by Modulating Renal Organic Transporters MATE-1 and OCT-2
por: Freitas-Lima, Leandro Ceotto, et al.
Publicado: (2020)

Drug-Drug Interactions at Organic Cation Transporter 1
por: Zhou, Shiwei, et al.
Publicado: (2021)

A Physiologically-Based Pharmacokinetic Model of Trimethoprim for MATE1, OCT1, OCT2, and CYP2C8 Drug–Drug–Gene Interaction Predictions
por: Türk, Denise, et al.
Publicado: (2020)

Are assortative mating and genital divergence driven by reinforcement?
por: Hollander, Johan, et al.
Publicado: (2018)

Evolutionary divergence in competitive mating success through female mating bias for good genes
por: Dugand, Robert J., et al.
Publicado: (2018)

Divergent Selection and the Evolution of Signal Traits and Mating Preferences
por: Rundle, Howard D, et al.
Publicado: (2005)

Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice
por: He, Rui, et al.
Publicado: (2016)

Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K
por: Kantauskaitė, Marta, et al.
Publicado: (2020)

Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter
por: Moss, Darren M., et al.
Publicado: (2015)

Diversification under sexual selection: the relative roles of mate preference strength and the degree of divergence in mate preferences
por: Rodríguez, Rafael L, et al.
Publicado: (2013)

MsYSL6, A Metal Transporter Gene of Alfalfa, Increases Iron Accumulation and Benefits Cadmium Resistance
por: Zhang, Miao, et al.
Publicado: (2023)

Correction: Divergent Selection and the Evolution of Signal Traits and Mating Preferences
Publicado: (2014)

Comparative Sperm Proteomics in Mouse Species with Divergent Mating Systems
por: Vicens, Alberto, et al.
Publicado: (2017)

Divergence in Transcriptional and Regulatory Responses to Mating in Male and Female Fruitflies
por: Fowler, Emily K., et al.
Publicado: (2019)

Bioaccumulation of Cadmium Affects Development, Mating Behavior, and Fecundity in the Asian Corn Borer, Ostrinia furnacalis
por: Luo, Mei, et al.
Publicado: (2019)

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats
por: Jeong, Yoo-Seong, et al.
Publicado: (2019)

PPARα-Dependent Modulation by Metformin of the Expression of OCT-2 and MATE-1 in the Kidney of Mice
por: Arruda, Adriano Cleis, et al.
Publicado: (2020)

Evaluation of the potential drug interactions mediated through P‐gp, OCT2, and MATE1/2K with filgotinib in healthy subjects
por: Hsueh, Chia‐Hsiang, et al.
Publicado: (2021)

Extensive Divergence Between Mating-Type Chromosomes of the Anther-Smut Fungus
por: Hood, Michael E., et al.
Publicado: (2013)

EVOLUTION OF DIVERGENT FEMALE MATING PREFERENCE IN RESPONSE TO EXPERIMENTAL SEXUAL SELECTION
por: Debelle, Allan, et al.
Publicado: (2014)

The Poly-Glutamate Motif of GmMATE4 Regulates Its Isoflavone Transport Activity
por: Ku, Yee-Shan, et al.
Publicado: (2022)

Sly-miR398 Participates in Cadmium Stress Acclimation by Regulating Antioxidant System and Cadmium Transport in Tomato (Solanum lycopersicum)
por: Yan, Guochao, et al.
Publicado: (2023)

A Whole-Body Physiologically Based Pharmacokinetic Model Characterizing Interplay of OCTs and MATEs in Intestine, Liver and Kidney to Predict Drug-Drug Interactions of Metformin with Perpetrators
por: Yang, Yiting, et al.
Publicado: (2021)

Effects of cadmium exposure on intestinal microflora of Cipangopaludina cathayensis
por: Jiang, Jiao-yun, et al.
Publicado: (2022)

Cadmium transport and tolerance in rice: perspectives for reducing grain cadmium accumulation
por: Uraguchi, Shimpei, et al.
Publicado: (2012)

The chemical form of cadmium in subcellular fractions following cadmium exposure.
por: Waku, K
Publicado: (1984)

Divergent male and female mate preferences do not explain incipient speciation between lizard lineages
por: McLean, Claire A, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7mh8jnn5ivhqj26lsr1kakm0bn