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Membrane Environment Modulates Ligand-Binding Propensity of P2Y12 Receptor

The binding of natural ligands and synthetic drugs to the P2Y12 receptor is of great interest because of its crucial role in platelets activation and the therapy of arterial thrombosis. Up to now, all computational studies of P2Y12 concentrated on the available crystal structures, while the role of...

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Detalles Bibliográficos
Autores principales:	Haghighi, Fatemeh, Yesylevskyy, Semen, Davani, Siamak, Ramseyer, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069422/ https://www.ncbi.nlm.nih.gov/pubmed/33918934 http://dx.doi.org/10.3390/pharmaceutics13040524

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