Thiosemicarbazide Derivatives Decrease the ATPase Activity of Staphylococcus aureus Topoisomerase IV, Inhibit Mycobacterial Growth, and Affect Replication in Mycobacterium smegmatis

Compounds targeting bacterial topoisomerases are of interest for the development of antibacterial agents. Our previous studies culminated in the synthesis and characterization of small-molecular weight thiosemicarbazides as the initial prototypes of a novel class of gyrase and topoisomerase IV inhib...

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Detalles Bibliográficos
Autores principales: Kowalczyk, Aleksandra, Paneth, Agata, Trojanowski, Damian, Paneth, Piotr, Zakrzewska-Czerwińska, Jolanta, Stączek, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069432/
https://www.ncbi.nlm.nih.gov/pubmed/33918623
http://dx.doi.org/10.3390/ijms22083881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069432/
https://www.ncbi.nlm.nih.gov/pubmed/33918623
http://dx.doi.org/10.3390/ijms22083881

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