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Improved One-Class Modeling of High-Dimensional Metabolomics Data via Eigenvalue-Shrinkage
One-class modelling is a useful approach in metabolomics for the untargeted detection of abnormal metabolite profiles, when information from a set of reference observations is available to model “normal” or baseline metabolite profiles. Such outlying profiles are typically identified by comparing th...
Autores principales: | Brini, Alberto, Avagyan, Vahe, de Vos, Ric C. H., Vossen, Jack H., van den Heuvel, Edwin R., Engel, Jasper |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069634/ https://www.ncbi.nlm.nih.gov/pubmed/33924479 http://dx.doi.org/10.3390/metabo11040237 |
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