Cargando…

Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus species with a zoonotic origin and responsible for the coronavirus disease 2019(COVID-19). This novel virus has an extremely high infectious rate, which occurs through the contact of contaminat...

Descripción completa

Detalles Bibliográficos
Autores principales: Sivasankarapillai, Vishnu Sankar, Madaswamy, Suba Lakshmi, Dhanusuraman, Ragupathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069635/
https://www.ncbi.nlm.nih.gov/pubmed/34766054
http://dx.doi.org/10.1016/j.sintl.2021.100096
_version_ 1783683283409698816
author Sivasankarapillai, Vishnu Sankar
Madaswamy, Suba Lakshmi
Dhanusuraman, Ragupathy
author_facet Sivasankarapillai, Vishnu Sankar
Madaswamy, Suba Lakshmi
Dhanusuraman, Ragupathy
author_sort Sivasankarapillai, Vishnu Sankar
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus species with a zoonotic origin and responsible for the coronavirus disease 2019(COVID-19). This novel virus has an extremely high infectious rate, which occurs through the contact of contaminated surfaces and also by cough, sneeze, hand-to-mouth-to-eye contact with an affected person. The progression of infection, which goes beyond complications of pneumonia to affecting other physiological functions which cause gastrointestinal, Renal, and neurological complication makes this a life threatening condition. Intense efforts are going across the scientific community in elucidating various aspects of this virus, such as understanding the pathophysiology of the disease, molecular biology, and cellular pathways of viral replication. We hope that nanotechnology and material science can provide a significant contribution to tackle this problem through both diagnostic and therapeutic strategies. But the area is still in the budding phase, which needs urgent and significant attention. This review provides a brief idea regarding the various nanotechnological approaches reported for managing COVID-19 infection. The nanomaterials recently said to have good antiviral activities like Carbon nanotubes (CNTs) and quantum dots (QDs) were also discussed since they are also in the emerging stage of attaining research interest regarding antiviral applications.
format Online
Article
Text
id pubmed-8069635
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.
record_format MEDLINE/PubMed
spelling pubmed-80696352021-04-26 Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver Sivasankarapillai, Vishnu Sankar Madaswamy, Suba Lakshmi Dhanusuraman, Ragupathy Sens Int Article Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus species with a zoonotic origin and responsible for the coronavirus disease 2019(COVID-19). This novel virus has an extremely high infectious rate, which occurs through the contact of contaminated surfaces and also by cough, sneeze, hand-to-mouth-to-eye contact with an affected person. The progression of infection, which goes beyond complications of pneumonia to affecting other physiological functions which cause gastrointestinal, Renal, and neurological complication makes this a life threatening condition. Intense efforts are going across the scientific community in elucidating various aspects of this virus, such as understanding the pathophysiology of the disease, molecular biology, and cellular pathways of viral replication. We hope that nanotechnology and material science can provide a significant contribution to tackle this problem through both diagnostic and therapeutic strategies. But the area is still in the budding phase, which needs urgent and significant attention. This review provides a brief idea regarding the various nanotechnological approaches reported for managing COVID-19 infection. The nanomaterials recently said to have good antiviral activities like Carbon nanotubes (CNTs) and quantum dots (QDs) were also discussed since they are also in the emerging stage of attaining research interest regarding antiviral applications. The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. 2021 2021-04-25 /pmc/articles/PMC8069635/ /pubmed/34766054 http://dx.doi.org/10.1016/j.sintl.2021.100096 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sivasankarapillai, Vishnu Sankar
Madaswamy, Suba Lakshmi
Dhanusuraman, Ragupathy
Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver
title Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver
title_full Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver
title_fullStr Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver
title_full_unstemmed Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver
title_short Role of nanotechnology in facing SARS-CoV-2 pandemic: Solving crux of the matter with a hopeful arrow in the quiver
title_sort role of nanotechnology in facing sars-cov-2 pandemic: solving crux of the matter with a hopeful arrow in the quiver
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069635/
https://www.ncbi.nlm.nih.gov/pubmed/34766054
http://dx.doi.org/10.1016/j.sintl.2021.100096
work_keys_str_mv AT sivasankarapillaivishnusankar roleofnanotechnologyinfacingsarscov2pandemicsolvingcruxofthematterwithahopefularrowinthequiver
AT madaswamysubalakshmi roleofnanotechnologyinfacingsarscov2pandemicsolvingcruxofthematterwithahopefularrowinthequiver
AT dhanusuramanragupathy roleofnanotechnologyinfacingsarscov2pandemicsolvingcruxofthematterwithahopefularrowinthequiver