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Overview of the Therapeutic Potential of Aptamers Targeting Coagulation Factors
Aptamers are single-stranded DNA or RNA sequences that bind target molecules with high specificity and affinity. Aptamers exhibit several notable advantages over protein-based therapeutics. Aptamers are non-immunogenic, easier to synthesize and modify, and can bind targets with greater affinity. Due...
Autores principales: | Liu, Max, Zaman, Khalequz, Fortenberry, Yolanda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069679/ https://www.ncbi.nlm.nih.gov/pubmed/33918821 http://dx.doi.org/10.3390/ijms22083897 |
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