DYRK1A Negatively Regulates CDK5-SOX2 Pathway and Self-Renewal of Glioblastoma Stem Cells

Glioblastoma display vast cellular heterogeneity, with glioblastoma stem cells (GSCs) at the apex. The critical role of GSCs in tumour growth and resistance to therapy highlights the need to delineate mechanisms that control stemness and differentiation potential of GSC. Dual-specificity tyrosine ph...

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Detalles Bibliográficos
Autores principales: Chen, Brianna, McCuaig-Walton, Dylan, Tan, Sean, Montgomery, Andrew P., Day, Bryan W., Kassiou, Michael, Munoz, Lenka, Recasens, Ariadna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069695/
https://www.ncbi.nlm.nih.gov/pubmed/33924599
http://dx.doi.org/10.3390/ijms22084011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069695/
https://www.ncbi.nlm.nih.gov/pubmed/33924599
http://dx.doi.org/10.3390/ijms22084011

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