BF(3)-OEt(2) Catalyzed C3-Alkylation of Indole: Synthesis of Indolylsuccinimidesand Their Cytotoxicity Studies

A simple and efficient BF(3)-OEt(2) promoted C3-alkylation of indole has been developed to obtain3-indolylsuccinimidesfrom commercially available indoles and maleimides, with excellent yields under mild reaction conditions. Furthermore, anti-proliferative activity of these conjugates was evaluated a...

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Detalles Bibliográficos
Autores principales: Shaikh, Iqbal N., Rahim, Abdul, Faazil, Shaikh, Adil, Syed Farooq, Assal, Mohamed E., Hatshan, Mohammad Rafe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069703/
https://www.ncbi.nlm.nih.gov/pubmed/33920456
http://dx.doi.org/10.3390/molecules26082202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069703/
https://www.ncbi.nlm.nih.gov/pubmed/33920456
http://dx.doi.org/10.3390/molecules26082202

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