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Clinically Relevant Concentrations of Polymyxin B and Meropenem Synergistically Kill Multidrug-Resistant Pseudomonas aeruginosa and Minimize Biofilm Formation
The emergence of antibiotic resistance has severely impaired the treatment of chronic respiratory infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa. Since the reintroduction of polymyxins as a last-line therapy against MDR Gram-negative bacteria, resistance to its monotherapy and...
Autores principales: | Wickremasinghe, Hasini, Yu, Heidi H., Azad, Mohammad A. K., Zhao, Jinxin, Bergen, Phillip J., Velkov, Tony, Zhou, Qi Tony, Zhu, Yan, Li, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069709/ https://www.ncbi.nlm.nih.gov/pubmed/33918040 http://dx.doi.org/10.3390/antibiotics10040405 |
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