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Simultaneous Expression of Th1- and Treg-Associated Chemokine Genes and CD4(+), CD8(+), and Foxp3(+) Cells in the Premalignant Lesions of 4NQO-Induced Mouse Tongue Tumorigenesis

SIMPLE SUMMARY: Oral squamous cell carcinoma (OSCC), the most common oral malignancy, severely impacts patient quality of life because of oro-facial destruction. OSCC is preceded by oral premalignant lesions (OPLs). Moreover, lower T cell infiltration in OPLs is associated with OSCC, suggesting that...

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Detalles Bibliográficos
Autores principales:	Yamaguchi, Hana, Hiroi, Miki, Mori, Kazumasa, Ushio, Ryosuke, Matsumoto, Ari, Yamamoto, Nobuharu, Shimada, Jun, Ohmori, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069711/ https://www.ncbi.nlm.nih.gov/pubmed/33921389 http://dx.doi.org/10.3390/cancers13081835

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