Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design

Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with “small...

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Detalles Bibliográficos
Autores principales: Huang, Rui, Luther, David C., Zhang, Xianzhi, Gupta, Aarohi, Tufts, Samantha A., Rotello, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069843/
https://www.ncbi.nlm.nih.gov/pubmed/33924735
http://dx.doi.org/10.3390/nano11041001
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author Huang, Rui
Luther, David C.
Zhang, Xianzhi
Gupta, Aarohi
Tufts, Samantha A.
Rotello, Vincent M.
author_facet Huang, Rui
Luther, David C.
Zhang, Xianzhi
Gupta, Aarohi
Tufts, Samantha A.
Rotello, Vincent M.
author_sort Huang, Rui
collection PubMed
description Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with “small” organic ligands (Mw < 1000), providing insight into how organic synthesis can be used to engineer NPs for nanobiology and nanomedicine.
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spelling pubmed-80698432021-04-26 Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design Huang, Rui Luther, David C. Zhang, Xianzhi Gupta, Aarohi Tufts, Samantha A. Rotello, Vincent M. Nanomaterials (Basel) Review Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with “small” organic ligands (Mw < 1000), providing insight into how organic synthesis can be used to engineer NPs for nanobiology and nanomedicine. MDPI 2021-04-13 /pmc/articles/PMC8069843/ /pubmed/33924735 http://dx.doi.org/10.3390/nano11041001 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Huang, Rui
Luther, David C.
Zhang, Xianzhi
Gupta, Aarohi
Tufts, Samantha A.
Rotello, Vincent M.
Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
title Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
title_full Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
title_fullStr Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
title_full_unstemmed Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
title_short Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
title_sort engineering the interface between inorganic nanoparticles and biological systems through ligand design
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069843/
https://www.ncbi.nlm.nih.gov/pubmed/33924735
http://dx.doi.org/10.3390/nano11041001
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