Rapamycin Alleviates 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Aggravated Dermatitis in Mice with Imiquimod-Induced Psoriasis-Like Dermatitis by Inducing Autophagy

Recently, the mTOR signaling has emerged as an important player in the pathogenesis of psoriasis. We previously found that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced psoriatic skin inflammation was related to the inhibition of autophagy in keratinocytes. However, the effects and detailed mol...

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Detalles Bibliográficos
Autores principales: Kim, Hye Ran, Kim, Jin Cheol, Kang, Seok Young, Kim, Hye One, Park, Chun Wook, Chung, Bo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069848/
https://www.ncbi.nlm.nih.gov/pubmed/33921372
http://dx.doi.org/10.3390/ijms22083968

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