Cargando…
Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa
Resistance is threatening the effectiveness of insecticide-based interventions in use for malaria control. Pinpointing genes associated with resistance is crucial for evidence-based resistance management targeting the major malaria vectors. Here, a combination of RNA-seq based genome-wide transcript...
Autores principales: | Kouamo, Mersimine F. M., Ibrahim, Sulaiman S., Hearn, Jack, Riveron, Jacob M., Kusimo, Michael, Tchouakui, Magellan, Ebai, Terence, Tchapga, Williams, Wondji, Murielle J., Irving, Helen, Boudjeko, Thaddée, Boyom, Fabrice F., Wondji, Charles S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069850/ https://www.ncbi.nlm.nih.gov/pubmed/33924421 http://dx.doi.org/10.3390/genes12040561 |
Ejemplares similares
-
Fitness Costs of the Glutathione S-Transferase Epsilon 2 (L119F-GSTe2) Mediated Metabolic Resistance to Insecticides in the Major African Malaria Vector Anopheles Funestus
por: Tchouakui, Magellan, et al.
Publicado: (2018) -
A marker of glutathione S-transferase-mediated resistance to insecticides is associated with higher Plasmodium infection in the African malaria vector Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2019) -
An Experimental Hut Evaluation of PBO-Based and Pyrethroid-Only Nets against the Malaria Vector Anopheles funestus Reveals a Loss of Bed Nets Efficacy Associated with GSTe2 Metabolic Resistance
por: Menze, Benjamin D., et al.
Publicado: (2020) -
Investigation of the influence of a glutathione S-transferase metabolic resistance to pyrethroids/DDT on mating competitiveness in males of the African malaria vector,
Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2019) -
Escalation of Pyrethroid Resistance in the Malaria Vector Anopheles funestus Induces a Loss of Efficacy of Piperonyl Butoxide–Based Insecticide-Treated Nets in Mozambique
por: Riveron, Jacob M, et al.
Publicado: (2019)