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Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review

The analysis of controlled drugs in forensic matrices, i.e., urine, blood, plasma, saliva, and hair, is one of the current hot topics in the clinical and toxicological context. The use of microextraction-based approaches has gained considerable notoriety, mainly due to the great simplicity, cost-ben...

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Autores principales: Ahmad, Samir M., Gonçalves, Oriana C., Oliveira, Mariana N., Neng, Nuno R., Nogueira, José M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070059/
https://www.ncbi.nlm.nih.gov/pubmed/33918766
http://dx.doi.org/10.3390/molecules26082168
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author Ahmad, Samir M.
Gonçalves, Oriana C.
Oliveira, Mariana N.
Neng, Nuno R.
Nogueira, José M. F.
author_facet Ahmad, Samir M.
Gonçalves, Oriana C.
Oliveira, Mariana N.
Neng, Nuno R.
Nogueira, José M. F.
author_sort Ahmad, Samir M.
collection PubMed
description The analysis of controlled drugs in forensic matrices, i.e., urine, blood, plasma, saliva, and hair, is one of the current hot topics in the clinical and toxicological context. The use of microextraction-based approaches has gained considerable notoriety, mainly due to the great simplicity, cost-benefit, and environmental sustainability. For this reason, the application of these innovative techniques has become more relevant than ever in programs for monitoring priority substances such as the main illicit drugs, e.g., opioids, stimulants, cannabinoids, hallucinogens, dissociative drugs, and related compounds. The present contribution aims to make a comprehensive review on the state-of-the art advantages and future trends on the application of microextraction-based techniques for screening-controlled drugs in the forensic context.
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spelling pubmed-80700592021-04-26 Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review Ahmad, Samir M. Gonçalves, Oriana C. Oliveira, Mariana N. Neng, Nuno R. Nogueira, José M. F. Molecules Review The analysis of controlled drugs in forensic matrices, i.e., urine, blood, plasma, saliva, and hair, is one of the current hot topics in the clinical and toxicological context. The use of microextraction-based approaches has gained considerable notoriety, mainly due to the great simplicity, cost-benefit, and environmental sustainability. For this reason, the application of these innovative techniques has become more relevant than ever in programs for monitoring priority substances such as the main illicit drugs, e.g., opioids, stimulants, cannabinoids, hallucinogens, dissociative drugs, and related compounds. The present contribution aims to make a comprehensive review on the state-of-the art advantages and future trends on the application of microextraction-based techniques for screening-controlled drugs in the forensic context. MDPI 2021-04-09 /pmc/articles/PMC8070059/ /pubmed/33918766 http://dx.doi.org/10.3390/molecules26082168 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ahmad, Samir M.
Gonçalves, Oriana C.
Oliveira, Mariana N.
Neng, Nuno R.
Nogueira, José M. F.
Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review
title Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review
title_full Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review
title_fullStr Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review
title_full_unstemmed Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review
title_short Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review
title_sort application of microextraction-based techniques for screening-controlled drugs in forensic context—a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070059/
https://www.ncbi.nlm.nih.gov/pubmed/33918766
http://dx.doi.org/10.3390/molecules26082168
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