BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets

Central nervous system tumor with BCL6-corepressor internal tandem duplication (CNS-BCOR ITD) is a malignant entity characterized by recurrent alterations in exon 15 encoding the essential binding domain for the polycomb repressive complex (PRC). In contrast to deletion or truncating mutations seen...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakata, Satoshi, Yuan, Ming, Rubens, Jeffrey A., Kahlert, Ulf D., Maciaczyk, Jarek, Raabe, Eric H., Eberhart, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070097/
https://www.ncbi.nlm.nih.gov/pubmed/33920124
http://dx.doi.org/10.3390/ijms22083913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070097/
https://www.ncbi.nlm.nih.gov/pubmed/33920124
http://dx.doi.org/10.3390/ijms22083913

Ejemplares similares