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BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets

Central nervous system tumor with BCL6-corepressor internal tandem duplication (CNS-BCOR ITD) is a malignant entity characterized by recurrent alterations in exon 15 encoding the essential binding domain for the polycomb repressive complex (PRC). In contrast to deletion or truncating mutations seen...

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Detalles Bibliográficos
Autores principales:	Nakata, Satoshi, Yuan, Ming, Rubens, Jeffrey A., Kahlert, Ulf D., Maciaczyk, Jarek, Raabe, Eric H., Eberhart, Charles G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070097/ https://www.ncbi.nlm.nih.gov/pubmed/33920124 http://dx.doi.org/10.3390/ijms22083913

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