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A Perspective on COVID-19 Management

A novel coronavirus—Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)—outbreak correlated with the global coronavirus disease 2019 (COVID-19) pandemic was declared by the WHO in March 2020, resulting in numerous counted cases attributed to SARS-CoV-2 worldwide. Herein, we discuss current...

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Autores principales: Pavelić, Krešimir, Kraljević Pavelić, Sandra, Brix, Bianca, Goswami, Nandu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070140/
https://www.ncbi.nlm.nih.gov/pubmed/33918624
http://dx.doi.org/10.3390/jcm10081586
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author Pavelić, Krešimir
Kraljević Pavelić, Sandra
Brix, Bianca
Goswami, Nandu
author_facet Pavelić, Krešimir
Kraljević Pavelić, Sandra
Brix, Bianca
Goswami, Nandu
author_sort Pavelić, Krešimir
collection PubMed
description A novel coronavirus—Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)—outbreak correlated with the global coronavirus disease 2019 (COVID-19) pandemic was declared by the WHO in March 2020, resulting in numerous counted cases attributed to SARS-CoV-2 worldwide. Herein, we discuss current knowledge on the available therapy options for patients diagnosed with COVID-19. Based on available scientific data, we present an overview of solutions in COVID-19 management by use of drugs, vaccines and antibodies. Many questions with non-conclusive answers on the measures for the management of the COVID-19 pandemic and its impact on health still exist—i.e., the actual infection percentage of the population, updated precise mortality data, variability in response to infection by the population, the nature of immunity and its duration, vaccine development issues, a fear that science might end up with excessive promises in response to COVID-19—and were raised among scientists. Indeed, science may or may not deliver results in real time. In the presented paper we discuss some consequences of disease, its detection and serological tests, some solutions to disease prevention and management, pitfalls and obstacles, including vaccination. The presented ideas and data herein are meant to contribute to the ongoing debate on COVID-19 without pre-selection of available information.
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spelling pubmed-80701402021-04-26 A Perspective on COVID-19 Management Pavelić, Krešimir Kraljević Pavelić, Sandra Brix, Bianca Goswami, Nandu J Clin Med Review A novel coronavirus—Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)—outbreak correlated with the global coronavirus disease 2019 (COVID-19) pandemic was declared by the WHO in March 2020, resulting in numerous counted cases attributed to SARS-CoV-2 worldwide. Herein, we discuss current knowledge on the available therapy options for patients diagnosed with COVID-19. Based on available scientific data, we present an overview of solutions in COVID-19 management by use of drugs, vaccines and antibodies. Many questions with non-conclusive answers on the measures for the management of the COVID-19 pandemic and its impact on health still exist—i.e., the actual infection percentage of the population, updated precise mortality data, variability in response to infection by the population, the nature of immunity and its duration, vaccine development issues, a fear that science might end up with excessive promises in response to COVID-19—and were raised among scientists. Indeed, science may or may not deliver results in real time. In the presented paper we discuss some consequences of disease, its detection and serological tests, some solutions to disease prevention and management, pitfalls and obstacles, including vaccination. The presented ideas and data herein are meant to contribute to the ongoing debate on COVID-19 without pre-selection of available information. MDPI 2021-04-09 /pmc/articles/PMC8070140/ /pubmed/33918624 http://dx.doi.org/10.3390/jcm10081586 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pavelić, Krešimir
Kraljević Pavelić, Sandra
Brix, Bianca
Goswami, Nandu
A Perspective on COVID-19 Management
title A Perspective on COVID-19 Management
title_full A Perspective on COVID-19 Management
title_fullStr A Perspective on COVID-19 Management
title_full_unstemmed A Perspective on COVID-19 Management
title_short A Perspective on COVID-19 Management
title_sort perspective on covid-19 management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070140/
https://www.ncbi.nlm.nih.gov/pubmed/33918624
http://dx.doi.org/10.3390/jcm10081586
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