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Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017

BACKGROUND: Female breast cancer (FBC) is a malignancy involving multiple risk factors and has imposed heavy disease burden on women. We aim to analyze the secular trends of mortality rate of FBC according to its major risk factors. METHODS: Death data of FBC at the global, regional, and national le...

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Autores principales: Liu, Hui, Shi, Wenjie, Jin, Zhi, Zhuo, Rui, Dong, Jie, Lao, Qiufeng, Li, Shengle, Pang, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070325/
https://www.ncbi.nlm.nih.gov/pubmed/33894746
http://dx.doi.org/10.1186/s12885-021-08217-5
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author Liu, Hui
Shi, Wenjie
Jin, Zhi
Zhuo, Rui
Dong, Jie
Lao, Qiufeng
Li, Shengle
Pang, Weiyi
author_facet Liu, Hui
Shi, Wenjie
Jin, Zhi
Zhuo, Rui
Dong, Jie
Lao, Qiufeng
Li, Shengle
Pang, Weiyi
author_sort Liu, Hui
collection PubMed
description BACKGROUND: Female breast cancer (FBC) is a malignancy involving multiple risk factors and has imposed heavy disease burden on women. We aim to analyze the secular trends of mortality rate of FBC according to its major risk factors. METHODS: Death data of FBC at the global, regional, and national levels were retrieved from the online database of Global Burden of Disease study 2017. Deaths of FBC attributable to alcohol use, high body-mass index (BMI), high fasting plasma glucose (FPG), low physical activity, and tobacco were collected. Estimated average percentage change (EAPC) was used to quantify the temporal trends of age-standardized mortality rate (ASMR) of FBC in 1990–2017. RESULTS: Worldwide, the number of deaths from FBC increased from 344.9 thousand in 1990 to 600.7 thousand in 2017. The ASMR of FBC decreased by 0.59% (95% CI, 0.52, 0.66%) per year during the study period. This decrease was largely driven by the reduction in alcohol use- and tobacco-related FBC, of which the ASMR was decreased by 1.73 and 1.77% per year, respectively. In contrast, the ASMR of FBC attributable to high BMI and high FPG was increased by 1.26% (95% CI, 1.22, 1.30%) and 0.26% (95% CI, 0.23, 0.30%) per year between 1990 and 2017, respectively. CONCLUSIONS: The mortality rate of FBC experienced a reduction over the last three decades, which was partly owing to the effective control for alcohol and tobacco use. However, more potent and tailored prevention strategies for obesity and diabetes are urgently warranted. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12885-021-08217-5.
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spelling pubmed-80703252021-04-26 Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017 Liu, Hui Shi, Wenjie Jin, Zhi Zhuo, Rui Dong, Jie Lao, Qiufeng Li, Shengle Pang, Weiyi BMC Cancer Research BACKGROUND: Female breast cancer (FBC) is a malignancy involving multiple risk factors and has imposed heavy disease burden on women. We aim to analyze the secular trends of mortality rate of FBC according to its major risk factors. METHODS: Death data of FBC at the global, regional, and national levels were retrieved from the online database of Global Burden of Disease study 2017. Deaths of FBC attributable to alcohol use, high body-mass index (BMI), high fasting plasma glucose (FPG), low physical activity, and tobacco were collected. Estimated average percentage change (EAPC) was used to quantify the temporal trends of age-standardized mortality rate (ASMR) of FBC in 1990–2017. RESULTS: Worldwide, the number of deaths from FBC increased from 344.9 thousand in 1990 to 600.7 thousand in 2017. The ASMR of FBC decreased by 0.59% (95% CI, 0.52, 0.66%) per year during the study period. This decrease was largely driven by the reduction in alcohol use- and tobacco-related FBC, of which the ASMR was decreased by 1.73 and 1.77% per year, respectively. In contrast, the ASMR of FBC attributable to high BMI and high FPG was increased by 1.26% (95% CI, 1.22, 1.30%) and 0.26% (95% CI, 0.23, 0.30%) per year between 1990 and 2017, respectively. CONCLUSIONS: The mortality rate of FBC experienced a reduction over the last three decades, which was partly owing to the effective control for alcohol and tobacco use. However, more potent and tailored prevention strategies for obesity and diabetes are urgently warranted. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12885-021-08217-5. BioMed Central 2021-04-24 /pmc/articles/PMC8070325/ /pubmed/33894746 http://dx.doi.org/10.1186/s12885-021-08217-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Liu, Hui
Shi, Wenjie
Jin, Zhi
Zhuo, Rui
Dong, Jie
Lao, Qiufeng
Li, Shengle
Pang, Weiyi
Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
title Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
title_full Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
title_fullStr Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
title_full_unstemmed Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
title_short Global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
title_sort global, regional, and national mortality trends of female breast cancer by risk factor, 1990–2017
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070325/
https://www.ncbi.nlm.nih.gov/pubmed/33894746
http://dx.doi.org/10.1186/s12885-021-08217-5
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