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Structural Characterization of a Minimal Antibody against Human APOBEC3B
APOBEC3B (A3B) is one of seven human APOBEC3 DNA cytosine deaminases that restrict viral infections as part of the overall innate immune response, but it also plays a major role in tumor evolution by mutating genomic DNA. Given the importance of A3B as a restriction factor of viral infections and as...
Autores principales: | Tang, Heng, Demir, Özlem, Kurniawan, Fredy, Brown, William L., Shi, Ke, Moeller, Nicholas H., Carpenter, Michael A., Belica, Christopher, Orellana, Kayo, Du, Guocheng, LeBeau, Aaron M., Amaro, Rommie E., Harris, Reuben S., Aihara, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070380/ https://www.ncbi.nlm.nih.gov/pubmed/33921405 http://dx.doi.org/10.3390/v13040663 |
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