Cargando…

Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain

Alzheimer’s disease (AD) is the most predominant age-related neurodegenerative disease, pathologically characterized by the accumulation of aggregates of amyloid beta Aβ(1–42) and tau hyperphosphorylation in the brain. It is considered to be the primary cause of cognitive dysfunction. The aggregatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rehman, Inayat Ur, Ahmad, Riaz, Khan, Ibrahim, Lee, Hyeon Jin, Park, Jungsung, Ullah, Rahat, Choi, Myeong Jun, Kang, Hee Young, Kim, Myeong Ok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070416/ https://www.ncbi.nlm.nih.gov/pubmed/33920212 http://dx.doi.org/10.3390/biomedicines9040408

Ejemplares similares

Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson’s Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways
por: Rehman, Inayat Ur, et al.
Publicado: (2022)

Lupeol, a Plant-Derived Triterpenoid, Protects Mice Brains against Aβ-Induced Oxidative Stress and Neurodegeneration
por: Ahmad, Riaz, et al.
Publicado: (2020)

Glycine, the smallest amino acid, confers neuroprotection against d-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain
por: Ullah, Rahat, et al.
Publicado: (2020)

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling
por: Muhammad, Tahir, et al.
Publicado: (2019)

Alpha-Linolenic Acid Impedes Cadmium-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration in Mouse Brain
por: Alam, Sayed-Ibrar, et al.
Publicado: (2021)

Nicotinamide Inhibits Alkylating Agent-Induced Apoptotic Neurodegeneration in the Developing Rat Brain
por: Ullah, Najeeb, et al.
Publicado: (2011)

Lupeol Treatment Attenuates Activation of Glial Cells and Oxidative-Stress-Mediated Neuropathology in Mouse Model of Traumatic Brain Injury
por: Ahmad, Riaz, et al.
Publicado: (2022)

Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling
por: Rehman, Shafiq Ur, et al.
Publicado: (2019)

17β-Estradiol Abrogates Oxidative Stress and Neuroinflammation after Cortical Stab Wound Injury
por: Saeed, Kamran, et al.
Publicado: (2021)

Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and neurodegeneration in postnatal rat brain
por: Shah, Shahid Ali, et al.
Publicado: (2016)

Pharmacological Inhibition of Spleen Tyrosine Kinase Suppressed Neuroinflammation and Cognitive Dysfunction in LPS-Induced Neurodegeneration Model
por: Kim, Min Woo, et al.
Publicado: (2022)

Natural Antioxidant Anthocyanins—A Hidden Therapeutic Candidate in Metabolic Disorders with Major Focus in Neurodegeneration
por: Ullah, Rahat, et al.
Publicado: (2019)

Vanillic Acid, a Bioactive Phenolic Compound, Counteracts LPS-Induced Neurotoxicity by Regulating c-Jun N-Terminal Kinase in Mouse Brain
por: Ullah, Rahat, et al.
Publicado: (2020)

Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson’s Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment
por: Atiq, Abubakar, et al.
Publicado: (2023)

Quinpirole-Mediated Regulation of Dopamine D2 Receptors Inhibits Glial Cell-Induced Neuroinflammation in Cortex and Striatum after Brain Injury
por: Alam, Sayed Ibrar, et al.
Publicado: (2021)

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus
por: Ali, Tahir, et al.
Publicado: (2015)

Nicotinamide Improves Functional Recovery via Regulation of the RAGE/JNK/NF-κB Signaling Pathway after Brain Injury
por: Alam, Sayed Ibrar, et al.
Publicado: (2019)

A Triterpenoid Lupeol as an Antioxidant and Anti-Neuroinflammatory Agent: Impacts on Oxidative Stress in Alzheimer’s Disease
por: Park, Jun Sung, et al.
Publicado: (2023)

Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model
por: Saeed, Kamran, et al.
Publicado: (2020)

Systematic Review of the Common Pathophysiological Mechanisms in COVID-19 and Neurodegeneration: The Role of Bioactive Compounds and Natural Antioxidants
por: Choe, Kyonghwan, et al.
Publicado: (2022)

Melatonin as a Potential Regulator of Oxidative Stress, and Neuroinflammation: Mechanisms and Implications for the Management of Brain Injury-Induced Neurodegeneration
por: Ikram, Muhammad, et al.
Publicado: (2021)

Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment
por: Ahmad, Ashfaq, et al.
Publicado: (2019)

Dietary Supplementation of the Antioxidant Curcumin Halts Systemic LPS-Induced Neuroinflammation-Associated Neurodegeneration and Memory/Synaptic Impairment via the JNK/NF-κB/Akt Signaling Pathway in Adult Rats
por: Khan, Muhammad Sohail, et al.
Publicado: (2019)

Ongoing Research on the Role of Gintonin in the Management of Neurodegenerative Disorders
por: Ikram, Muhammad, et al.
Publicado: (2020)

Succinamide Derivatives Ameliorate Neuroinflammation and Oxidative Stress in Scopolamine-Induced Neurodegeneration
por: Iqbal, Sumbal, et al.
Publicado: (2020)

Metformin attenuate PTZ-induced apoptotic neurodegeneration in human cortical neuronal cells
por: Bibi, Fehmida, et al.
Publicado: (2017)

Inhibition of JNK Alleviates Chronic Hypoperfusion-Related Ischemia Induces Oxidative Stress and Brain Degeneration via Nrf2/HO-1 and NF-κB Signaling
por: Khan, Muhammad Sohail, et al.
Publicado: (2020)

A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye
por: Sarkar, Ankita, et al.
Publicado: (2018)

Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons
por: Ullah, Ikram, et al.
Publicado: (2012)

Oral Administration of Alpha Linoleic Acid Rescues Aβ-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice
por: Ali, Waqar, et al.
Publicado: (2020)

Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling
por: Ikram, Muhammad, et al.
Publicado: (2019)

Molecular Cloning and Expression of Osmotin in a Baculovirus-Insect System: Purified Osmotin Mitigates Amyloid-beta Deposition in Neuronal Cells
por: Abid, Noman Bin, et al.
Publicado: (2017)

Iron, Neuroinflammation and Neurodegeneration
por: Ward, Roberta J., et al.
Publicado: (2022)

17-β Estradiol Rescued Immature Rat Brain against Glutamate-Induced Oxidative Stress and Neurodegeneration via Regulating Nrf2/HO-1 and MAP-Kinase Signaling Pathway
por: Khan, Ibrahim, et al.
Publicado: (2021)

Editorial: Pharmacological approaches towards the resolution of neuroinflammation and neurodegeneration
por: Liang, Huazheng, et al.
Publicado: (2023)

Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration
por: Cheng, Shanshan, et al.
Publicado: (2015)

Nicotinamide and WLD(S) Act Together to Prevent Neurodegeneration in Glaucoma
por: Williams, Pete A., et al.
Publicado: (2017)

Nicotinamide Reduces Amyloid Precursor Protein and Presenilin 1 in Brain Tissues of Amyloid Beta-Tail Vein Injected Mice
por: Kim, Eun Jin, et al.
Publicado: (2017)

CD38 in Neurodegeneration and Neuroinflammation
por: Guerreiro, Serge, et al.
Publicado: (2020)

Neuroinflammation and neurodegeneration in diabetic retinopathy
por: Bianco, Lorenzo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g0ecps0qh85l7ktkl31842t7h3