Facile Synthesis and In Vitro Activity of N-Substituted 1,2-Benzisothiazol-3(2H)-ones against Dengue Virus NS2BNS3 Protease

Several new N-substituted 1,2-benzisothiazol-3(2H)-ones (BITs) were synthesised through a facile synthetic route for testing their anti-dengue protease inhibition. Contrary to the conventional multistep synthesis, we achieved structurally diverse BITs with excellent yields using a two-step, one-pot...

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Detalles Bibliográficos
Autores principales: Batool, Farwa, Saeed, Muhammad, Saleem, Hafiza Nosheen, Kirschner, Luisa, Bodem, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070447/
https://www.ncbi.nlm.nih.gov/pubmed/33921368
http://dx.doi.org/10.3390/pathogens10040464

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