Cargando…

Widespread Alternative Splicing Changes in Metastatic Breast Cancer Cells

Aberrant alternative splicing (AS) is a hallmark of cancer and a potential target for novel anti-cancer therapeutics. Breast cancer-associated AS events are known to be linked to disease progression, metastasis, and survival of breast cancer patients. To identify altered AS programs occurring in met...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oh, Jagyeong, Pradella, Davide, Shao, Changwei, Li, Hairi, Choi, Namjeong, Ha, Jiyeon, Ruggiero, Sonia, Fu, Xiang-Dong, Zheng, Xuexiu, Ghigna, Claudia, Shen, Haihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070448/ https://www.ncbi.nlm.nih.gov/pubmed/33918758 http://dx.doi.org/10.3390/cells10040858

Ejemplares similares

Global Alternative Splicing Defects in Human Breast Cancer Cells
por: Oh, Jagyeong, et al.
Publicado: (2021)

Opposite Roles of Tra2β and SRSF9 in the v10 Exon Splicing of CD44
por: Oh, Jagyeong, et al.
Publicado: (2020)

Relative strength of 5’ splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA
por: Choi, Namjeong, et al.
Publicado: (2021)

U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing
por: Choi, Namjeong, et al.
Publicado: (2020)

SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon
por: Ha, Jiyeon, et al.
Publicado: (2021)

hnRNP A1 Regulates Alternative Splicing of Tau Exon 10 by Targeting 3′ Splice Sites
por: Liu, Yongchao, et al.
Publicado: (2020)

SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence
por: Choi, Namjeong, et al.
Publicado: (2022)

Activation of Cryptic 3′ Splice-Sites by SRSF2 Contributes to Cassette Exon Skipping
por: Moon, Heegyum, et al.
Publicado: (2019)

RRM but not the Asp/Glu domain of hnRNP C(1)/C(2) is required for splicing regulation of Ron exon 11 pre-mRNA
por: Moon, Heegyum, et al.
Publicado: (2019)

SRSF2 directly inhibits intron splicing to suppresses cassette exon inclusion
por: Moon, Heegyum, et al.
Publicado: (2017)

EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression
por: Pradella, Davide, et al.
Publicado: (2017)

Alternative splicing in endothelial cells: novel therapeutic opportunities in cancer angiogenesis
por: Di Matteo, Anna, et al.
Publicado: (2020)

Diversification of the muscle proteome through alternative splicing
por: Nakka, Kiran, et al.
Publicado: (2018)

Alternative Splicing and Tumor Progression
por: Ghigna, Claudia, et al.
Publicado: (2008)

Gene Expression Profiles Controlled by the Alternative Splicing Factor Nova2 in Endothelial Cells
por: Belloni, Elisa, et al.
Publicado: (2019)

Alternative Splicing: Role in Cancer Development and Progression
por: Sette, Claudio, et al.
Publicado: (2013)

Alternative Splicing: Recent Insights into Mechanisms and Functional Roles
por: Ghigna, Claudia, et al.
Publicado: (2020)

SR proteins regulate V(6) exon splicing of CD44 pre-mRNA
por: Loh, Tiing Jen, et al.
Publicado: (2016)

Identification of Regulatory-RNAs for Alternative Splicing of Ron Proto-Oncogene
por: Moon, Heegyum, et al.
Publicado: (2015)

Phylogenetically widespread alternative splicing at unusual GYNGYN donors
por: Hiller, Michael, et al.
Publicado: (2006)

Widespread alternative and aberrant splicing revealed by lariat sequencing
por: Stepankiw, Nicholas, et al.
Publicado: (2015)

Alternative Splicing Changes Promoted by NOVA2 Upregulation in Endothelial Cells and Relevance for Gastric Cancer
por: Di Matteo, Anna, et al.
Publicado: (2023)

Oncogenic Alternative Splicing Switches: Role in Cancer Progression and Prospects for Therapy
por: Bonomi, Serena, et al.
Publicado: (2013)

Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer
por: Siegfried, Zahava, et al.
Publicado: (2013)

The alternative splicing factor Nova2 regulates vascular development and lumen formation
por: Giampietro, Costanza, et al.
Publicado: (2015)

Widespread Use of Non-productive Alternative Splice Sites in Saccharomyces cerevisiae
por: Kawashima, Tadashi, et al.
Publicado: (2014)

Spliced Leader Trapping Reveals Widespread Alternative Splicing Patterns in the Highly Dynamic Transcriptome of Trypanosoma brucei
por: Nilsson, Daniel, et al.
Publicado: (2010)

Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer
por: Han, Jian, et al.
Publicado: (2022)

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
por: Rogelj, Boris, et al.
Publicado: (2012)

A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing
por: Angiolini, Francesca, et al.
Publicado: (2019)

A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene
por: MOON, HEEGYUM, et al.
Publicado: (2014)

Widespread Aberrant Alternative Splicing despite Molecular Remission in Chronic Myeloid Leukaemia Patients
por: Schmitz, Ulf, et al.
Publicado: (2020)

SAM68: Signal Transduction and RNA Metabolism in Human Cancer
por: Frisone, Paola, et al.
Publicado: (2015)

Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators
por: Qiu, Jinsong, et al.
Publicado: (2016)

Noncoding RNAs regulate alternative splicing in Cancer
por: Liu, Yunze, et al.
Publicado: (2021)

Polypyrimidine tract binding protein inhibits IgM pre-mRNA splicing by diverting U2 snRNA base-pairing away from the branch point
por: Zheng, Xuexiu, et al.
Publicado: (2014)

Long-read RNA sequencing reveals widespread sex-specific alternative splicing in threespine stickleback fish
por: Naftaly, Alice S., et al.
Publicado: (2021)

Sam68 regulates EMT through alternative splicing–activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene
por: Valacca, Cristina, et al.
Publicado: (2010)

Identification of neoantigens derived from alternative splicing and RNA modification
por: Park, Jiyeon, et al.
Publicado: (2019)

The Identification of Prognostic and Metastatic Alternative Splicing in Skin Cutaneous Melanoma
por: Huang, Runzhi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ieqr140hkbj2apqr01ue2b53r3