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Therapeutic Efficacy of a Novel Acetylated Tetrapeptide in Animal Models of Age-Related Macular Degeneration

It has been shown previously that a novel tetrapeptide, Arg-Leu-Tyr-Glu (RLYE), derived from human plasminogen inhibits vascular endothelial growth factor (VEGF)-induced angiogenesis, suppresses choroidal neovascularization in mice by an inhibition of VEGF receptor-2 (VEGFR-2) specific signaling pat...

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Detalles Bibliográficos
Autores principales: Koo, Hye Cheong, Baek, Yi-Yong, Choi, Jun-Sup, Kim, Young-Myeong, Sung, Bokyung, Kim, Min-Jung, Kim, Jae Gyu, You, Ji Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070582/
https://www.ncbi.nlm.nih.gov/pubmed/33918777
http://dx.doi.org/10.3390/ijms22083893