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Therapeutic Efficacy of a Novel Acetylated Tetrapeptide in Animal Models of Age-Related Macular Degeneration
It has been shown previously that a novel tetrapeptide, Arg-Leu-Tyr-Glu (RLYE), derived from human plasminogen inhibits vascular endothelial growth factor (VEGF)-induced angiogenesis, suppresses choroidal neovascularization in mice by an inhibition of VEGF receptor-2 (VEGFR-2) specific signaling pat...
Autores principales: | Koo, Hye Cheong, Baek, Yi-Yong, Choi, Jun-Sup, Kim, Young-Myeong, Sung, Bokyung, Kim, Min-Jung, Kim, Jae Gyu, You, Ji Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070582/ https://www.ncbi.nlm.nih.gov/pubmed/33918777 http://dx.doi.org/10.3390/ijms22083893 |
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