Inhibiting FAK–Paxillin Interaction Reduces Migration and Invadopodia-Mediated Matrix Degradation in Metastatic Melanoma Cells

SIMPLE SUMMARY: The focal adhesion kinase (FAK) is over-expressed in a variety of human tumors and is involved in many aspects of the metastatic process. This has led to the development of small inhibitors of FAK kinase function which are currently evaluated in clinical trials. We demonstrate here t...

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Detalles Bibliográficos
Autores principales: Mousson, Antoine, Legrand, Marlène, Steffan, Tania, Vauchelles, Romain, Carl, Philippe, Gies, Jean-Pierre, Lehmann, Maxime, Zuber, Guy, De Mey, Jan, Dujardin, Denis, Sick, Emilie, Rondé, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070677/
https://www.ncbi.nlm.nih.gov/pubmed/33919725
http://dx.doi.org/10.3390/cancers13081871

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