Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer

SIMPLE SUMMARY: Small-cell lung cancer accounts for approximately 13% of all new lung cancer diagnoses, but in contrast to non-small-cell lung cancer, the implementation of targeted treatments in small-cell lung cancer has been limited, with little improvement in the clinical outcome in the last sev...

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Detalles Bibliográficos
Autores principales: Coll-SanMartin, Laia, Davalos, Veronica, Piñeyro, David, Rosselló-Tortella, Margalida, Bueno-Costa, Alberto, Setien, Fernando, Villanueva, Alberto, Granada, Isabel, Ruiz-Xiviller, Neus, Kotter, Annika, Helm, Mark, Yokota, Jun, Kawabata-Iwakawa, Reika, Kohno, Takashi, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070726/
https://www.ncbi.nlm.nih.gov/pubmed/33919717
http://dx.doi.org/10.3390/cancers13081869

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