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Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells
Carnosic acid (CA), carnosol (CL) and rosmarinic acid (RA), components of the herb rosemary, reportedly exert favorable metabolic actions. This study showed that both CA and CL, but not RA, induce significant phosphorylation of AMP-dependent kinase (AMPK) and its downstream acetyl-CoA carboxylase 1...
Autores principales: | Hasei, Shun, Yamamotoya, Takeshi, Nakatsu, Yusuke, Ohata, Yukino, Itoga, Shota, Nonaka, Yuji, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Asano, Tomoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070802/ https://www.ncbi.nlm.nih.gov/pubmed/33919842 http://dx.doi.org/10.3390/ijms22084040 |
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