Cargando…

Recombinant IGF-1 Induces Sex-Specific Changes in Bone Composition and Remodeling in Adult Mice with Pappa2 Deficiency

Deficiency of pregnancy-associated plasma protein-A2 (PAPP-A2), an IGF-1 availability regulator, causes postnatal growth failure and dysregulation of bone size and density. The present study aimed to determine the effects of recombinant murine IGF-1 (rmIGF-1) on bone composition and remodeling in co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rubio, Leticia, Vargas, Antonio, Rivera, Patricia, López-Gambero, Antonio J., Tovar, Rubén, Christians, Julian K., Martín-de-las-Heras, Stella, Rodríguez de Fonseca, Fernando, Chowen, Julie A., Argente, Jesús, Suárez, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070906/ https://www.ncbi.nlm.nih.gov/pubmed/33919940 http://dx.doi.org/10.3390/ijms22084048

Ejemplares similares

Pappa2 deletion in mice affects male but not female fertility
por: Christians, Julian K., et al.
Publicado: (2015)

Altered placental expression of PAPPA2 does not affect birth weight in mice
por: Wagner, Pamela K, et al.
Publicado: (2010)

PAPPA2 as a Therapeutic Modulator of IGF-I Bioavailability: in Vivo and in Vitro Evidence
por: Andrew, Melissa, et al.
Publicado: (2018)

Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR
por: Sifakis, Stavros, et al.
Publicado: (2018)

Analysis of Both Lipid Metabolism and Endocannabinoid Signaling Reveals a New Role for Hypothalamic Astrocytes in Maternal Caloric Restriction-Induced Perinatal Programming
por: Tovar, Rubén, et al.
Publicado: (2021)

Regulation of pregnancy-associated plasma protein A2 (PAPPA2) in a human placental trophoblast cell line (BeWo)
por: Wagner, Pamela K, et al.
Publicado: (2011)

Partners in Postmortem Interval Estimation: X-ray Diffraction and Fourier Transform Spectroscopy
por: Rubio, Leticia, et al.
Publicado: (2023)

One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology
por: Argente, Jesús, et al.
Publicado: (2017)

Symposium on Aspect of Nuclear Science : Festschrift Pappas (Alexis Constantin)
por: Hagebo, Einar, et al.
Publicado: (1987)

The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats
por: Decara, Juan, et al.
Publicado: (2018)

Leptin Modulates the Response of Brown Adipose Tissue to Negative Energy Balance: Implication of the GH/IGF-I Axis
por: Barrios, Vicente, et al.
Publicado: (2021)

A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins
por: Bøtkjær, Jane Alrø, et al.
Publicado: (2019)

Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model
por: Rivera, Patricia, et al.
Publicado: (2020)

MON-LB083 The Dimorphic Effects of Short-Term Dietary Changes on the Central and Circulating IGF1 System in Rats
por: Guerra Cantera, Santiago, et al.
Publicado: (2019)

Dental color measurement to predict DNA concentration in incinerated teeth for human identification
por: Rubio, Leticia, et al.
Publicado: (2018)

Impact of Long-Term HFD Intake on the Peripheral and Central IGF System in Male and Female Mice
por: Guerra-Cantera, Santiago, et al.
Publicado: (2020)

Pregnancy-associated plasma protein-A (PAPPA) promotes breast cancer progression
por: Zhang, Jun, et al.
Publicado: (2022)

Short-Term Diet Induced Changes in the Central and Circulating IGF Systems Are Sex Specific
por: Guerra-Cantera, Santiago, et al.
Publicado: (2020)

Pathophysiology of Vascular Remodeling in Hypertension
por: Renna, Nicolás F., et al.
Publicado: (2013)

A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer’s Disease, the 5XFAD Mouse
por: López-Gambero, Antonio J., et al.
Publicado: (2021)

Spectrophotometric Color Measurement to Assess Temperature of Exposure in Cortical and Medullar Heated Human Bones: A Preliminary Study
por: Rubio, Leticia, et al.
Publicado: (2020)

Author Correction: A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins
por: Bøtkjær, J. A., et al.
Publicado: (2019)

Ontogeny of Expression and Activity of Digestive Enzymes and Establishment of gh/igf1 Axis in the Omnivorous Fish Chelon labrosus
por: Gilannejad, Neda, et al.
Publicado: (2020)

Novel Prognostic Biomarkers in Gastric Cancer: CGB5, MKNK2, and PAPPA2
por: Qin, Min, et al.
Publicado: (2021)

Generation and Application of Inducible Chimeric RNA ASTN2-PAPPA(as) Knockin Mouse Model
por: Luo, Yichen, et al.
Publicado: (2022)

PAPPA Expression in Indeterminate Thyroid Nodules as Screening Test to Select Patients for Molecular Testing
por: Marzocchi, Carlotta, et al.
Publicado: (2022)

d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?
por: Medina‐Vera, Dina, et al.
Publicado: (2022)

Sex-Dependent Altered Expression of Cannabinoid Signaling in Hippocampal Astrocytes of the Triple Transgenic Mouse Model of Alzheimer’s Disease: Implications for Controlling Astroglial Activity
por: Pacheco-Sánchez, Beatriz, et al.
Publicado: (2023)

Total Knee Replacement Arthroplasty with Buechel and Pappas Knee: Minimum 2-Year Follow-up
por: Moon, Kyoung Ho, et al.
Publicado: (2015)

Genetic Study of IL6, GDF5 and PAPPA2 in Association with Developmental Dysplasia of the Hip
por: Harsanyi, Stefan, et al.
Publicado: (2021)

Propensity score analysis of psychological intimate partner violence and preterm birth
por: Martín-de-las-Heras, Stella, et al.
Publicado: (2022)

DNA degradation in human teeth exposed to thermal stress
por: Lozano-Peral, Diego, et al.
Publicado: (2021)

Role of Non-Neuronal Cells in Body Weight and Appetite Control
por: Argente-Arizón, Pilar, et al.
Publicado: (2015)

Plasma Concentrations of BDNF and IGF-1 in Abstinent Cocaine Users with High Prevalence of Substance Use Disorders: Relationship to Psychiatric Comorbidity
por: Pedraz, María, et al.
Publicado: (2015)

Effects of Maternal Resveratrol Intake on the Metabolic Health of the Offspring
por: Ros, Purificación, et al.
Publicado: (2021)

Microglial Proliferation in Obesity: When, Where, Why, and What Does It Mean?
por: Chowen, Julie A., et al.
Publicado: (2017)

Sex differences in adipose tissue: It is not only a question of quantity and distribution
por: Fuente-Martín, Esther, et al.
Publicado: (2013)

Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases
por: Decara, Juan, et al.
Publicado: (2020)

A Replication Study for the Association of rs726252 in PAPPA2 with Developmental Dysplasia of the Hip in Chinese Han Population
por: Shi, Dongquan, et al.
Publicado: (2014)

Placental DNA methylation at term reflects maternal serum levels of INHA and FN1, but not PAPPA, early in pregnancy
por: Wilson, Samantha L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_t30qpf14tq44il1k70ufpj5fd9