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Disulfiram Abrogates Morphine Tolerance—A Possible Role of µ-Opioid Receptor-Related G-Protein Activation in the Striatum

One of the key strategies for effective pain management involves delaying analgesic tolerance. Early clinical reports indicate an extraordinary effectiveness of off-label disulfiram—an agent designed for alcohol use disorder—in potentiating opioid analgesia and abrogation of tolerance. Our study aim...

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Detalles Bibliográficos
Autores principales:	de Corde-Skurska, Anna, Krzascik, Pawel, Lesniak, Anna, Sacharczuk, Mariusz, Nagraba, Lukasz, Bujalska-Zadrozny, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071001/ https://www.ncbi.nlm.nih.gov/pubmed/33919998 http://dx.doi.org/10.3390/ijms22084057

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