Cargando…
Natural Product Inhibition and Enzyme Kinetics Related to Phylogenetic Characterization for Bacterial Peptidyl-tRNA Hydrolase 1
With the relentless development of drug resistance and re-emergence of many pathogenic bacteria, the need for new antibiotics and new antibiotic targets is urgent and growing. Bacterial peptidyl-tRNA hydrolase, Pth1, is emerging as a promising new target for antibiotic development. From the conserve...
Autores principales: | Strange, D. Scott, Gaffin, Steven S., Holloway, W. Blake, Kinsella, Meredyth D., Wisotsky, Jacob N., McFeeters, Hana, McFeeters, Robert L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071115/ https://www.ncbi.nlm.nih.gov/pubmed/33920799 http://dx.doi.org/10.3390/molecules26082281 |
Ejemplares similares
-
Small Molecule Binding, Docking, and Characterization of the Interaction between Pth1 and Peptidyl-tRNA
por: Hames, Mary C., et al.
Publicado: (2013) -
Expedited isolation of natural product peptidyl-tRNA hydrolase inhibitors from a Pth1 affinity column
por: Sethi, Harkirat S., et al.
Publicado: (2017) -
Small Molecule Docking Supports Broad and Narrow Spectrum Potential for the Inhibition of the Novel Antibiotic Target Bacterial Pth1
por: Ferguson, Paul P., et al.
Publicado: (2016) -
Novel Antifungal Activity for the Lectin Scytovirin: Inhibition of Cryptococcus neoformans and Cryptococcus gattii
por: Jones, Tyler H., et al.
Publicado: (2017) -
Bigger Data Approach to Analysis of Essential Oils and Their Antifungal Activity against Aspergillus niger, Candida albicans, and Cryptococcus neoformans
por: Powers, Chelsea N., et al.
Publicado: (2019)