Design and Synthesis of 2,6-Disubstituted-4′-Selenoadenosine-5′-N,N-Dimethyluronamide Derivatives as Human A(3) Adenosine Receptor Antagonists

A new series of 4′-selenoadenosine-5′-N,N-dimethyluronamide derivatives as highly potent and selective human A(3) adenosine receptor (hA(3)AR) antagonists, is described. The highly selective A(3)AR agonists, 4′-selenoadenosine-5′-N-methyluronamides were successfully converted into selective antagoni...

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Detalles Bibliográficos
Autores principales: Choi, Hongseok, Jacobson, Kenneth A., Yu, Jinha, Jeong, Lak Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071163/
https://www.ncbi.nlm.nih.gov/pubmed/33920062
http://dx.doi.org/10.3390/ph14040363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071163/
https://www.ncbi.nlm.nih.gov/pubmed/33920062
http://dx.doi.org/10.3390/ph14040363

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