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Design and Synthesis of 2,6-Disubstituted-4′-Selenoadenosine-5′-N,N-Dimethyluronamide Derivatives as Human A(3) Adenosine Receptor Antagonists
A new series of 4′-selenoadenosine-5′-N,N-dimethyluronamide derivatives as highly potent and selective human A(3) adenosine receptor (hA(3)AR) antagonists, is described. The highly selective A(3)AR agonists, 4′-selenoadenosine-5′-N-methyluronamides were successfully converted into selective antagoni...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071163/ https://www.ncbi.nlm.nih.gov/pubmed/33920062 http://dx.doi.org/10.3390/ph14040363 |