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Sildenafil 4.0—Integrated Synthetic Chemistry, Formulation and Analytical Strategies Effecting Immense Therapeutic and Societal Impact in the Fourth Industrial Era

Sildenafil is a potent selective, reversible inhibitor of phosphodiesterase type 5 (PDE5) approved for the treatment of erectile dysfunction and pulmonary arterial hypertension. Whilst twenty years have passed since its original approval by the US Food and Drug Administration (USFDA), sildenafil ent...

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Detalles Bibliográficos
Autores principales: Ouranidis, Andreas, Tsiaxerli, Anastasia, Vardaka, Elisavet, Markopoulou, Catherine K., Zacharis, Constantinos K., Nicolaou, Ioannis, Hatzichristou, Dimitris, Haidich, Anna-Bettina, Kostomitsopoulos, Nikolaos, Kachrimanis, Kyriakos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071249/
https://www.ncbi.nlm.nih.gov/pubmed/33920975
http://dx.doi.org/10.3390/ph14040365