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Sildenafil 4.0—Integrated Synthetic Chemistry, Formulation and Analytical Strategies Effecting Immense Therapeutic and Societal Impact in the Fourth Industrial Era
Sildenafil is a potent selective, reversible inhibitor of phosphodiesterase type 5 (PDE5) approved for the treatment of erectile dysfunction and pulmonary arterial hypertension. Whilst twenty years have passed since its original approval by the US Food and Drug Administration (USFDA), sildenafil ent...
Autores principales: | Ouranidis, Andreas, Tsiaxerli, Anastasia, Vardaka, Elisavet, Markopoulou, Catherine K., Zacharis, Constantinos K., Nicolaou, Ioannis, Hatzichristou, Dimitris, Haidich, Anna-Bettina, Kostomitsopoulos, Nikolaos, Kachrimanis, Kyriakos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071249/ https://www.ncbi.nlm.nih.gov/pubmed/33920975 http://dx.doi.org/10.3390/ph14040365 |
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