Chemoinformatics Studies on a Series of Imidazoles as Cruzain Inhibitors

Natural products based on imidazole scaffolds have inspired the discovery of a wide variety of bioactive compounds. Herein, a series of imidazoles that act as competitive and potent cruzain inhibitors was investigated using a combination of ligand- and structure-based drug design strategies. Quantit...

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Detalles Bibliográficos
Autores principales: Medeiros, Alex R., Ferreira, Leonardo L. G., de Souza, Mariana L., de Oliveira Rezende Junior, Celso, Espinoza-Chávez, Rocío Marisol, Dias, Luiz Carlos, Andricopulo, Adriano D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071344/
https://www.ncbi.nlm.nih.gov/pubmed/33920961
http://dx.doi.org/10.3390/biom11040579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071344/
https://www.ncbi.nlm.nih.gov/pubmed/33920961
http://dx.doi.org/10.3390/biom11040579

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