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Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells

SIMPLE SUMMARY: The anaplastic lymphoma kinase (ALK) and rearranged during transfection (RET) receptor tyrosine kinases (RTKs) are expressed in both the developing neural crest and the pediatric cancer neuroblastoma. Moreover, ALK is mutated in approximately 10% of neuroblastomas. Here, we investiga...

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Detalles Bibliográficos
Autores principales: Siaw, Joachim T., Gabre, Jonatan L., Uçkun, Ezgi, Vigny, Marc, Zhang, Wancun, Van den Eynden, Jimmy, Hallberg, Bengt, Palmer, Ruth H., Guan, Jikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071449/
https://www.ncbi.nlm.nih.gov/pubmed/33921066
http://dx.doi.org/10.3390/cancers13081909