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Deconstruction of Lignin: From Enzymes to Microorganisms

Lignocellulosic residues are low-cost abundant feedstocks that can be used for industrial applications. However, their recalcitrance currently makes lignocellulose use limited. In natural environments, microbial communities can completely deconstruct lignocellulose by synergistic action of a set of...

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Autores principales: Silva, Jéssica P., Ticona, Alonso R. P., Hamann, Pedro R. V., Quirino, Betania F., Noronha, Eliane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071518/
https://www.ncbi.nlm.nih.gov/pubmed/33921125
http://dx.doi.org/10.3390/molecules26082299
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author Silva, Jéssica P.
Ticona, Alonso R. P.
Hamann, Pedro R. V.
Quirino, Betania F.
Noronha, Eliane F.
author_facet Silva, Jéssica P.
Ticona, Alonso R. P.
Hamann, Pedro R. V.
Quirino, Betania F.
Noronha, Eliane F.
author_sort Silva, Jéssica P.
collection PubMed
description Lignocellulosic residues are low-cost abundant feedstocks that can be used for industrial applications. However, their recalcitrance currently makes lignocellulose use limited. In natural environments, microbial communities can completely deconstruct lignocellulose by synergistic action of a set of enzymes and proteins. Microbial degradation of lignin by fungi, important lignin degraders in nature, has been intensively studied. More recently, bacteria have also been described as able to break down lignin, and to have a central role in recycling this plant polymer. Nevertheless, bacterial deconstruction of lignin has not been fully elucidated yet. Direct analysis of environmental samples using metagenomics, metatranscriptomics, and metaproteomics approaches is a powerful strategy to describe/discover enzymes, metabolic pathways, and microorganisms involved in lignin breakdown. Indeed, the use of these complementary techniques leads to a better understanding of the composition, function, and dynamics of microbial communities involved in lignin deconstruction. We focus on omics approaches and their contribution to the discovery of new enzymes and reactions that impact the development of lignin-based bioprocesses.
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spelling pubmed-80715182021-04-26 Deconstruction of Lignin: From Enzymes to Microorganisms Silva, Jéssica P. Ticona, Alonso R. P. Hamann, Pedro R. V. Quirino, Betania F. Noronha, Eliane F. Molecules Review Lignocellulosic residues are low-cost abundant feedstocks that can be used for industrial applications. However, their recalcitrance currently makes lignocellulose use limited. In natural environments, microbial communities can completely deconstruct lignocellulose by synergistic action of a set of enzymes and proteins. Microbial degradation of lignin by fungi, important lignin degraders in nature, has been intensively studied. More recently, bacteria have also been described as able to break down lignin, and to have a central role in recycling this plant polymer. Nevertheless, bacterial deconstruction of lignin has not been fully elucidated yet. Direct analysis of environmental samples using metagenomics, metatranscriptomics, and metaproteomics approaches is a powerful strategy to describe/discover enzymes, metabolic pathways, and microorganisms involved in lignin breakdown. Indeed, the use of these complementary techniques leads to a better understanding of the composition, function, and dynamics of microbial communities involved in lignin deconstruction. We focus on omics approaches and their contribution to the discovery of new enzymes and reactions that impact the development of lignin-based bioprocesses. MDPI 2021-04-15 /pmc/articles/PMC8071518/ /pubmed/33921125 http://dx.doi.org/10.3390/molecules26082299 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Silva, Jéssica P.
Ticona, Alonso R. P.
Hamann, Pedro R. V.
Quirino, Betania F.
Noronha, Eliane F.
Deconstruction of Lignin: From Enzymes to Microorganisms
title Deconstruction of Lignin: From Enzymes to Microorganisms
title_full Deconstruction of Lignin: From Enzymes to Microorganisms
title_fullStr Deconstruction of Lignin: From Enzymes to Microorganisms
title_full_unstemmed Deconstruction of Lignin: From Enzymes to Microorganisms
title_short Deconstruction of Lignin: From Enzymes to Microorganisms
title_sort deconstruction of lignin: from enzymes to microorganisms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071518/
https://www.ncbi.nlm.nih.gov/pubmed/33921125
http://dx.doi.org/10.3390/molecules26082299
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