Substrate Specificity of Chimeric Enzymes Formed by Interchange of the Catalytic and Specificity Domains of the 5′-Nucleotidase UshA and the 3′-Nucleotidase CpdB

The 5′-nucleotidase UshA and the 3′-nucleotidase CpdB from Escherichia coli are broad-specificity phosphohydrolases with similar two-domain structures. Their N-terminal domains (UshA_Ndom and CpdB_Ndom) contain the catalytic site, and their C-terminal domains (UshA_Cdom and CpdB_Cdom) contain a subs...

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Detalles Bibliográficos
Autores principales: Cabezas, Alicia, López-Villamizar, Iralis, Costas, María Jesús, Cameselle, José Carlos, Ribeiro, João Meireles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071527/
https://www.ncbi.nlm.nih.gov/pubmed/33923386
http://dx.doi.org/10.3390/molecules26082307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071527/
https://www.ncbi.nlm.nih.gov/pubmed/33923386
http://dx.doi.org/10.3390/molecules26082307

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