Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition

Antiseizure medications (ASMs) are frequently implicated in T cell-mediated drug hypersensitivity reactions and cause skin tropic pathologies that range in severity from mild rashes to life-threatening systemic syndromes. During the acute stages of the more severe manifestations of these reactions,...

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Detalles Bibliográficos
Autores principales: Mifsud, Nicole A., Illing, Patricia T., Lai, Jeffrey W., Fettke, Heidi, Hensen, Luca, Huang, Ziyi, Rossjohn, Jamie, Vivian, Julian P., Kwan, Patrick, Purcell, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071863/
https://www.ncbi.nlm.nih.gov/pubmed/33912179
http://dx.doi.org/10.3389/fimmu.2021.653710

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