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Lack of Cell Cycle Inhibitor p21 and Low CD4(+) T Cell Suppression in Newborns After Exposure to IFN-β

Type I IFNs, such as interferon alpha and interferon beta, are key regulators of the adaptive immune response during infectious diseases. Type I IFNs are induced upon infection, bind interferon α/β receptors on T-cells and activate intracellular pathways. The activating and inhibitory consequences o...

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Detalles Bibliográficos
Autores principales:	Jans, Jop, Unger, Wendy W., Raeven, Elisabeth A. M., Simonetti, Elles R., Eleveld, Marc J., de Groot, Ronald, de Jonge, Marien I., Ferwerda, Gerben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071872/ https://www.ncbi.nlm.nih.gov/pubmed/33912177 http://dx.doi.org/10.3389/fimmu.2021.652965

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