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The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions

First-line antituberculosis (anti-TB) compounds have been considered as proven components of the Directly Observed Treatment-Short course (DOTS). Drug therapy against tuberculosis has been categorized as I, II, or III following the Revised National Tuberculosis Control Program guidelines. Anti-TB ar...

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Autores principales: Imam, Faisal, Sharma, Manju, Obaid Al-Harbi, Naif, Rashid Khan, Mohammad, Qamar, Wajhul, Iqbal, Muzaffar, Daud Ali, Mohammad, Ali, Nemat, Khalid Anwar, Md.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071916/
https://www.ncbi.nlm.nih.gov/pubmed/33911919
http://dx.doi.org/10.1016/j.sjbs.2021.02.004
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author Imam, Faisal
Sharma, Manju
Obaid Al-Harbi, Naif
Rashid Khan, Mohammad
Qamar, Wajhul
Iqbal, Muzaffar
Daud Ali, Mohammad
Ali, Nemat
Khalid Anwar, Md.
author_facet Imam, Faisal
Sharma, Manju
Obaid Al-Harbi, Naif
Rashid Khan, Mohammad
Qamar, Wajhul
Iqbal, Muzaffar
Daud Ali, Mohammad
Ali, Nemat
Khalid Anwar, Md.
author_sort Imam, Faisal
collection PubMed
description First-line antituberculosis (anti-TB) compounds have been considered as proven components of the Directly Observed Treatment-Short course (DOTS). Drug therapy against tuberculosis has been categorized as I, II, or III following the Revised National Tuberculosis Control Program guidelines. Anti-TB are drugs are quite common and show limited adverse effects. However, first-line anti-TB compounds mediated DOTS therapy and were found with several complications. Thus, those drugs have been discontinued. Therefore, the present study was designed to find out the possible impact of socioeconomic, income, and educational status on the adverse effects of drugs and their therapeutic episodes in patients targeted with a combination of tuberculosis intervention. This study found that an increased incidence of tuberculosis was found in patients who have finished high school, contributing to a high percentage of adverse effects. Notably, adverse events were shown maximally in poor patients compared with rich- or high-income patients. On the contrary, a high prevalence of adverse events was shown to be increased in partially skilled workers compared with full-skilled workers. Consequently, adversely considerable events were implicated to be raised in patients associated with minimal socioeconomic class. Such interesting factors would help in monitoring such events in experimental patients.
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spelling pubmed-80719162021-04-27 The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions Imam, Faisal Sharma, Manju Obaid Al-Harbi, Naif Rashid Khan, Mohammad Qamar, Wajhul Iqbal, Muzaffar Daud Ali, Mohammad Ali, Nemat Khalid Anwar, Md. Saudi J Biol Sci Original Article First-line antituberculosis (anti-TB) compounds have been considered as proven components of the Directly Observed Treatment-Short course (DOTS). Drug therapy against tuberculosis has been categorized as I, II, or III following the Revised National Tuberculosis Control Program guidelines. Anti-TB are drugs are quite common and show limited adverse effects. However, first-line anti-TB compounds mediated DOTS therapy and were found with several complications. Thus, those drugs have been discontinued. Therefore, the present study was designed to find out the possible impact of socioeconomic, income, and educational status on the adverse effects of drugs and their therapeutic episodes in patients targeted with a combination of tuberculosis intervention. This study found that an increased incidence of tuberculosis was found in patients who have finished high school, contributing to a high percentage of adverse effects. Notably, adverse events were shown maximally in poor patients compared with rich- or high-income patients. On the contrary, a high prevalence of adverse events was shown to be increased in partially skilled workers compared with full-skilled workers. Consequently, adversely considerable events were implicated to be raised in patients associated with minimal socioeconomic class. Such interesting factors would help in monitoring such events in experimental patients. Elsevier 2021-04 2021-02-14 /pmc/articles/PMC8071916/ /pubmed/33911919 http://dx.doi.org/10.1016/j.sjbs.2021.02.004 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Imam, Faisal
Sharma, Manju
Obaid Al-Harbi, Naif
Rashid Khan, Mohammad
Qamar, Wajhul
Iqbal, Muzaffar
Daud Ali, Mohammad
Ali, Nemat
Khalid Anwar, Md.
The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
title The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
title_full The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
title_fullStr The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
title_full_unstemmed The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
title_short The possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
title_sort possible impact of socioeconomic, income, and educational status on adverse effects of drug and their therapeutic episodes in patients targeted with a combination of tuberculosis interventions
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071916/
https://www.ncbi.nlm.nih.gov/pubmed/33911919
http://dx.doi.org/10.1016/j.sjbs.2021.02.004
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