Rapamycin Antagonizes BCRP-Mediated Drug Resistance Through the PI3K/Akt/mTOR Signaling Pathway in mPRα-Positive Breast Cancer

PURPOSE: Overexpression of breast cancer (BCa) resistance protein (BCRP) is detected in approximately 30% of BCa cases. BCRP indicates a poor response to chemotherapy, and it has become a classic target to overcome drug-resistant tumor cells. In this study, we aimed to explore the mechanism of BCRP...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Hu, Jing, Li, Weiwei, Zhang, Chunyan, Su, Peng, Wang, Yan, Sun, Wei, Wang, Xiao, Li, Li, Wu, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071953/
https://www.ncbi.nlm.nih.gov/pubmed/33912444
http://dx.doi.org/10.3389/fonc.2021.608570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071953/
https://www.ncbi.nlm.nih.gov/pubmed/33912444
http://dx.doi.org/10.3389/fonc.2021.608570

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