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Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System

Apelin receptor (APLNR/AGTRLl1/APJ) marks a transient cell population during the differentiation of hematopoietic stem and progenitor cells (HSPCs) from pluripotent stem cells, but its function during the production and maintenance of hematopoietic stem cells is not clear. We generated an Aplnr-tdTo...

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Detalles Bibliográficos
Autores principales: Jackson, Melany, Fidanza, Antonella, Taylor, A. Helen, Rybtsov, Stanislav, Axton, Richard, Kydonaki, Maria, Meek, Stephen, Burdon, Tom, Medvinsky, Alexander, Forrester, Lesley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072025/
https://www.ncbi.nlm.nih.gov/pubmed/33667414
http://dx.doi.org/10.1016/j.stemcr.2021.02.003

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