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Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System
Apelin receptor (APLNR/AGTRLl1/APJ) marks a transient cell population during the differentiation of hematopoietic stem and progenitor cells (HSPCs) from pluripotent stem cells, but its function during the production and maintenance of hematopoietic stem cells is not clear. We generated an Aplnr-tdTo...
Autores principales: | Jackson, Melany, Fidanza, Antonella, Taylor, A. Helen, Rybtsov, Stanislav, Axton, Richard, Kydonaki, Maria, Meek, Stephen, Burdon, Tom, Medvinsky, Alexander, Forrester, Lesley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072025/ https://www.ncbi.nlm.nih.gov/pubmed/33667414 http://dx.doi.org/10.1016/j.stemcr.2021.02.003 |
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