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Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells
CpG islands often exhibit low DNA methylation, high histone H3 lysine 4 trimethylation, low nucleosome density, and high DNase I hypersensitivity, yet the rules by which CpG islands are sensed remain poorly understood. In this study, we first evaluated the relationships between the DNA and the chrom...
Autores principales: | Langerman, Justin, Lopez, David, Pellegrini, Matteo, Smale, Stephen T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072027/ https://www.ncbi.nlm.nih.gov/pubmed/33770494 http://dx.doi.org/10.1016/j.stemcr.2021.02.016 |
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